Social Determinants of Neuro-Reproductive Health: Bridging Data Management, Equity, and Policy Intervention: Systematic Review

Neuro-reproductive health (NRH) encompasses the intricate interplay between the nervous, endocrine, and reproductive systems, influencing outcomes from fertility and pregnancy to neurodevelopment and menopausal transitions. This systematic review explores the profound impact of social determinants of health (SDH) on NRH disparities, highlighting the critical roles of effective data management, health equity principles, and targeted policy interventions. A comprehensive search of electronic databases (e.g., PubMed, Scopus, Web of Science) was conducted using keywords such as "social determinants", "neuro-reproductive health", "health equity", "data management", and "policy intervention". Studies consistently revealed that socioeconomic status, education, access to healthcare, environmental exposures, discrimination, and social support deeply influence NRH outcomes, often creating and exacerbating disparities across diverse populations. The review identifies significant gaps in current data management practices, emphasizing the need for integrated, interoperable, and ethically sound data collection to understand complex SDH-NRH pathways. It underscores that health equity must be the guiding principle for both data utilization and intervention design, moving beyond individual-level solutions to address systemic inequities. Finally, the synthesis proposes a multi-level policy framework, advocating for intersectoral collaboration, community engagement, and evidence-based strategies to mitigate the adverse effects of SDH on NRH and foster equitable health outcomes.